Early Treatment for COVID-19 and Post-Exposure Prophylaxis with Monoclonal Antibodies are available at the Monoclonal Antibody Regional Centers (MARCs)

What are Monoclonal Antibodies?

Monoclonal antibodies are proteins made in a lab that help boost the immune system to fight viruses. Monoclonal antibodies have been shown in clinical trials to reduce COVID-19-related hospitalizations and emergency room visits.

The monoclonal antibody combination treatment  has been authorized for emergency use by the FDA to treat mild to moderate COVID-19 in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progressing to severe COVID-19 and/or hospitalization. Treatment should be given within 10 days of symptom onset.

The monoclonal antibody combination treatment made by Regeneron, REGEN-COV, has also been authorized for emergency use by the FDA to help prevent persons from developing COVID-19 after they have been exposed to someone who is contagious with COVD-19. This is called post-exposure prophylaxis.

Monoclonal antibodies will be provided at no cost to medically eligible individuals regardless of health insurance or immigration status. 

Who Qualifies?


  • Health Providers
  • Patients
    • If you think that you are medically eligible (Spanish), call your primary care provider or healthcare system to request an appointment for monoclonal antibody therapy. 
    • If your primary care provider or healthcare system does not have monoclonal antibody therapy available, call (619) 685-2500 to ask questions or to schedule an appointment at the MARC. A provider referral is not required. 
    • Patients must wear a mask to their appointment.
  • Skilled Nursing Facilities 


  • MARC at Vista Community Clinic
    • Treatment site in Vista open Tuesday through Friday 
  • MARC at Clairemont Friendship Center
    • Treatment and post-exposure prophylaxis site in Clairemont open Monday through Saturday
  • Family Health Centers of San Diego
    • Treatment sites in Hillcrest and Chula Vista open Monday through Friday

Additional Resources

Questions? Email  COVIDtreatment@sdcounty.ca.gov