Mpox Vaccine

Page last updated 11/7/2023

See below, or click the following links, to learn more about:

Text COSD MPOX to 468-311.

Get text updates about mpox from the County. Text COSD MPOX to 468-311. (Phone users: tap to create the message)

What You Need to Know

MPOX Vaccine

Get your Mpox vaccine from a provider near you. Contact your healthcare provider or visit to schedule an appointment for your no-cost vaccine.

Click here for a list of County coordinated vaccination sites.

The Centers for Disease Control and Prevention (CDC) and the California Department of Public Health (CDPH) recommend vaccination for people who have been exposed to mpox and people who may be at risk for mpox. Persons who request vaccination should receive it without having to attest to specific risk factors.

Mpox vaccines are available at many locations. Visit the Mpox Vaccinations Schedule webpage for more information. 

About the JYNNEOS Vaccine

Vaccine Recommendations

Any person who may be at risk for mpox infection, or persons who request vaccination, may receive vaccination without having to report specific risk factors. Some individuals are at high risk for mpox infection and/or complications of mpox infection. They should be considered a priority and are strongly encouraged to receive the vaccination to decrease infection spread, minimize serious illness, and prevent facilities. This includes any of the following:

  • Anyone living with human immunodeficiency virus (HIV).
  • Any man or trans person who has sex with men or trans persons.
  • People who use or who are eligible for HIV pre-exposure prophylaxis (PrEP).
  • Sex workers.
  • Sexual partners of the above groups.
  • People who have had direct skin-to-skin contact with one or more people AND who know others in their community that have had mpox infection.
  • People who have been diagnosed with a bacterial sexually transmitted disease (STD) (e.g., chlamydia, gonorrhea, syphilis) in the past 3 months.
  • People who anticipate experiencing the above risks.

Known close contacts of people who have mpox should be vaccinated as soon as possible. This is called post-exposure prophylaxis (PEP). People in specific occupational groups should be offered vaccination.

 Vaccine-Related Frequently Asked Questions

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For more information, contact the Epidemiology Unit at (619) 692-8499 or send us an e-mail.